Cook your pasta according to the directions on the packaging in a large pot of salted water. Drain and set aside.
Cut your chicken in half lengthwise. Season the chicken with the jerk seasoning, garlic powder, onion powder, and pepper.
Heat olive oil in a large skillet over medium heat. Add the chicken and cook until browned and it reaches an internal temperature of 165°F, about 2 to 3 minutes per side. Transfer the chicken to a cutting board and set aside.
Trim the ends off your asparagus and cut into 1-inch chunks. Add the asparagus and mushrooms to the skillet and cook until tender. Transfer the vegetables to a plate and set aside.
Add the butter and garlic to the skillet and cook until fragrant, about one minute. Whisk in the heavy cream and Parmesan cheese, continuing to cook until it reaches your desired thickness.
Slice your chicken breast and add it to the skillet along with the pasta, asparagus, and mushrooms. Toss everything in the sauce and enjoy.